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Tang, Wei-Jen
One or more keywords matched the following items that are connected to Tang, Wei-Jen
Item TypeName
Concept Structure-Activity Relationship
Academic Article Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Academic Article Discovery of a small molecule that inhibits the interaction of anthrax edema factor with its cellular activator, calmodulin.
Academic Article Conversion of forskolin-insensitive to forskolin-sensitive (mouse-type IX) adenylyl cyclase.
Academic Article Structure of anthrax edema factor-calmodulin-adenosine 5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site.
Academic Article The conserved asparagine and arginine are essential for catalysis of mammalian adenylyl cyclase.
Academic Article Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Academic Article Adenylyl cyclases.
Academic Article Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening.
Academic Article Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.
Academic Article Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification.
Academic Article Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Academic Article Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-ß hydrolysis.
Academic Article Reinvestigating the synthesis and efficacy of small benzimidazole derivatives as presequence protease enhancers.
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